He was born March 19, 1963, in Saint Joseph, Manitoba, and ordained a priest in 1991 for the Archdiocese of Saint Boniface.
Benedict XVI named him bishop of Alexandria-Cornwall in 2012. Three years later, Pope Francis appointed him bishop of Sault Ste. Marie.
On May 6 this year, the pope announced that Damphousse would serve as coadjutor archbishop of Ottawa-Cornwall, alongside Prendergast.
Damphousse's inaugural Mass will take place on Dec. 8, the Solemnity of the Immaculate Conception. The Mass will be livestreamed due to coronavirus restrictions.
A tribute to Prendergast on Ottawa-Cornwall archdiocese's website said: "Archbishop Prendergast leaves a considerable legacy of accomplishments in the archdiocese. He is a staunch supporter of the pro-life movement, publicly opposing euthanasia and defending the life of the unborn."
"He has made the Church present to people at public events, greeting parishioners after every Mass and appearing at conferences locally and across the country. He encouraged Communion and Liberation to institute the Way of the Cross on Good Friday in the streets of Ottawa, as they had in Halifax."
"He was a columnist in the Catholic Register, the Ottawa Citizen, and the Ottawa Sun. He pioneered social media -- blogging, Facebook, Twitter and Instagram and has appeared on YouTube -- to reach a new generation."
Editor's note, 2020 Dec. 4 10:53 am: An earlier version of this story indicated that Archbishop Damphousse would also succeed Archbishop Prendergast as Apostolic Administrator of Hearst-Moosonee. It has been corrected.