Loading
Bone marrow stem cell therapy may halt multiple sclerosis
Facebook Twitter Google+ Pinterest Addthis

.- An experimental therapy using bone marrow stem cells stabilized and in some cases reversed early-phase multiple sclerosis, a new study reports.

Multiple sclerosis (MS) is an autoimmune disease that hinders movement and coordination and causes muscle weakness, cognitive impairment, slurred speech and vision problems.

In the decade or more after its onset, MS is characterized by gradual, irreversible neurological impairment. It has no known cure.

Richard Burt of Northwestern University in Chicago led a team of scientists in clinical trials for 11 women and 10 men who did not respond to standard drug treatments, according to a newly published report in the British medical journal The Lancet.

They “rebuilt” the patients’ immune systems, removing defective white blood cells that attack the fatty sheath or myelin that protects the nervous system.

The patients’ immune systems were then replenished with haemopoeitic stem cells extracted from the patients’ bone marrow. These specific stem cells are capable of giving rise to any form of mature blood cell.

After an average follow-up period of three years, 17 of the 21 patients improved by at least one point on a standard disability scale. None had a final score lower than they had before undergoing the stem cell therapy.

Five of the patients relapsed but achieved remission after receiving other immunosuppressive therapy, the Lancet study says.

Participants had MS for about five years. The clinical trials mark the first time the stem cell technique has been applied to young and relatively healthy individuals in the early “relapsing-remitting” stage of the disease.

The study also finds that the procedure “not only seems to prevent neurological progression, but also appears to reverse neurological disability.”

Gianluigi Mancardi of the University of Genoa in Italy wrote in a commentary in The Lancet that further trials are needed using control groups.

However, the results “imply that this is a valuable alternative to the transplant conditioning therapies used so far.”

MS affects millions worldwide, including almost 400,000 in the United States.

Ads by AdsLiveMedia(What's this?)

* The number of messages that can be online is limited. CNA reserves the right to edit messages for content and tone. Comments and opinions expressed by users do not necessarily reflect the opinions or beliefs of CNA. CNA will not publish comments with abusive language, insults or links to other pages

RESOURCES »

Ads by Google (What's this?)

Featured Videos

Christ Cathedral CNA video Sept 2014
Christ Cathedral CNA video Sept 2014
Alejandro Bermudez of CNA accepts ice bucket challenge
'The Real Albania,' remembering those who fled
Pope Francis in Albania, "one of the most important visits of the post-communist era in Albania"
Pope Francis greets paralyzed man who risked all to see him
Franciscans on the banks of the Tiber in Rome, working for the New Evangelization
Pilgrimage from Czech Republic to Assisi and Rome for intentions
Testimony of young Indian who met Pope in Korea
Preparations of the Closing Mass of 6th Asian Youth Day
Missionary of Charity, Korea
Testimony of Christian Love during Pope's Visit to Korea
Religious Sisters in South Korea react to Pope Francis kissing a baby
Warm atmosphere during Holy Mass at Daejeon World Cup Stadium
Images inside Pope Francis flight to South Korea
The tombs of the early Christians
Missionaries of Africa, called "the White Fathers"
Italian youth give testimony after mission to Peru
Interview with Iraqi Ambassador to the Holy See on the persecution of Christians
New book 'The Vatican unknown'
A Look at India from Rome
Sep
30

Liturgical Calendar

September 30, 2014

Saint Jerome, Priest and Doctor of the Church

All readings:
Today »
This year »

Catholic Daily

Gospel of the Day

Lk 9:51-56

Gospel
Date
09/30/14
09/29/14
09/28/14

Daily Readings


First Reading:: Job 3: 1-3, 11-17, 20-23
Gospel:: Lk 9: 51-56

Saint of the Day

St. Romuald »

Saint
Date
09/30/14

Homily of the Day

Lk 9:51-56

Homily
Date
09/30/14
09/29/14
09/28/14