Parolin also said that it should not come as a surprise that there is criticism of the deal between the Holy See and the Chinese government, as this is what "generally happens in complex issues and when one faces problems of great importance."
The agreement has been roundly criticized by human rights groups and some Church leaders, including Cardinal Joseph Zen Ze-kiun, Bishop Emeritus of Hong Kong.
Since the agreement was reached, there have been numerous instances of Catholic churches and shrines being demolished by government agents.
More recently, in the capital of Guangdong province, the Guangzhou Department of Ethnic and Religious Affairs offered a reward of 10,000 Chinese yuan (almost $1,500) for information on the activities of religious groups which could lead to the arrest of key leaders.
In March, U.S. ambassador-at-large for International Religious Freedom Sam Brownback said that "since this provisional deal [between the Vatican and China] was announced last year, the Chinese government's abuse of members of Catholic communities has continued. We see no signs that will change in the near future."
Parolin reiterated that dialogue is close to the heart of Pope Francis, who is particularly interested in dialogue on the pastoral level.
"The Holy Father asks Catholics in particular to undertake with courage the path of unity, reconciliation and a renewed proclamation of the Gospel. He sees China not only as a great country but also as a great culture, rich in history and wisdom," he said.
The Vatican Secretary of State pointed to the fight against poverty, environmental and climatic emergencies, migration, and ethical scientific development as global issues in which China and the Vatican can work together in a spirit of positive cooperation with "the dignity of the human person be placed at the center."
"The Holy See hopes that China will not be afraid to enter into dialogue with the wider world and that the world's nations will give credit to the profound aspirations of the Chinese people. In this way, with everyone working together, I am sure that we will be able to overcome mistrust and build a more secure and prosperous world," Parolin said.