"Maribel Trujillo's immigration case has undergone review at multiple levels of our nation's legal system and the courts have uniformly held that she has no legal basis to remain in the United States," the spokesperson said, according to the Cincinnati Enquirer.
Trujillo-Diaz became subject to deportation in 2014 when the Board of Immigration Appeals dismissed her appeals. Last year her lawyer filed an effort to re-hear her case, citing her father's kidnapping.
She was close to deportation in previous years. Thousands of area Catholics and other supporters rallied then to ask authorities to allow her to stay.
Last year, immigration officials, acting under prosecutorial discretion, decided she was low priority and no threat to public safety.
Her lawyer said at her March 6 check-in, officials implied they would seek her deportation.
"They told her, and this is exactly what they said: 'We have a new president now. I don't know if you are aware'," Kersh said.
"I think the Trump administration is only looking at numbers and not looking for those people who are criminals or are a threat to public safety," Kersh continued.
In a February letter, Archbishop Dennis M. Schnurr of Cincinnati had spoken on behalf of Trujillo-Lopez.
"Our church and our community gain nothing by being left with a single-parent household when such a responsible and well-respected family can be kept together," he said, citing Catholic teaching's emphasis on the family as "the highest organization of human society."
The archdiocese is asking Ohioans to contact U.S. Sen. Rob Portman (R-Ohio) and Gov. John Kasich to encourage them to ask Immigration and Customs Enforcement to stop Trujillo's deportation.