"We cannot be good Christians if we do not abide in Jesus. And yet with him, we can do everything," he underlined. "With him we can do everything."
"Let us entrust ourselves to the intercession of the Virgin Mary," he concluded. "She remained fully united to Jesus and bore much fruit. May she help us abide in Christ, in his love, in his word, to bear witness in the world to the Risen Lord."
At the end of the Regina caeli, Pope Francis sent his good wishes to Christians of the Orthodox Church and Eastern and Latin Catholic Churches, who celebrate Easter according to the Julian calendar, which falls this year on May 2.
"May the risen Lord fill them with light and peace, and comfort the communities living in particularly difficult situations. Happy Easter to them!" he said.
The pope also referenced the ongoing situation in Burma, where security forces have opened fire on people protesting the military coup, resulting in injuries and deaths.
He said the Church in Burma is encouraging everyone to devote one Hail Mary of their daily rosary during the month of May for peace in Burma.
"Each of us turns to our mother when he or she is in need or in difficulty," he said. "We, this month, ask our Heavenly Mother to speak to the hearts of all those responsible in Myanmar, so that they may find the courage to walk the path of encounter, reconciliation and peace."
Pope Francis also expressed his closeness to the people of Israel, where crowds at a Jewish religious festival on Mount Maron led to a crush of people resulting in 45 deaths and some 150 injuries the night of April 29 to April 30.
"I assure my remembrance in prayer for the victims of this tragedy and their families," he said.
Francis also mentioned the example of Bl. José Gregorio Hernández Cisneros, who was beatified in Caracas, Venezuela on April 30.
"He was a doctor, rich in science and faith. He was able to recognize the face of Christ in the sick and, as a good Samaritan, he helped them with evangelical charity. May his example help us to take care of those who suffer in body and spirit," he said, encouraging a round of applause for the new blessed.
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Hannah Brockhaus is Catholic News Agency's senior Rome correspondent. She grew up in Omaha, Nebraska, and has a degree in English from Truman State University in Missouri.