"Against this backdrop, the murder of George Floyd was like lighting a match in a gas-filled room," he said.
There is, however, cause for optimism even amidst these times, said Coakley.
"Injustice does not need to have the last word," he said. "The Lord came to free us from sin, including the sins by which we diminish workers and ourselves."
Coakley advised Catholics to be conscious consumers of the goods they purchase, and to consider the origins of the items and how companies treat their employees.
He also encouraged Congress and the White House to "reach a deal that prioritizes protecting the poor and vulnerable" as the government has played an "indispensable role" in addressing the various crises.
The archbishop further noted that the Catholic Campaign for Human Development, which turns 50 this year, has done much to alleviate the effects of the pandemic.
"The CCHD-supported Rural Community Workers Alliance has helped organize workers in rural Missouri, pressuring employers to take these concerns seriously and advancing the dignity of workers," he said. "These groups, as well as labor unions and other worker associations, make an invaluable contribution to the safety and wellbeing of workers."
Catholics, said Coakley, "are each called to practice solidarity with those in harm's way" in order to preserve worker's rights and their dignity. He encouraged people to donate to local food banks and Catholic Charities agencies.
"Pope Francis is fond of citing the 1964 dogmatic constitution, Lumen Gentium, which reminded us that 'no one can save themselves alone,'" said Coakley.
"This is true in this life and the next. The fruits of individualism are clear in the disparities brought to light by this crisis. Through our work of solidarity, let us be a counter-witness to individualism."